Anti-Aging
NAD+ Injection
Cellular energy & repair
This treatment requires licensed provider review and approval. Treatment is not guaranteed. If prescribed, medication is fulfilled by a licensed U.S. pharmacy where permitted by law. Compounded medications are not FDA-approved or FDA-cleared.
About NAD+ Injection
Direct NAD+ supplementation supports DNA repair, energy metabolism, and healthy aging.
How it works
NAD+ injections deliver nicotinamide adenine dinucleotide directly into circulation, bypassing oral bioavailability issues. NAD+ is essential for sirtuin activation, DNA repair, and cellular energy metabolism — all of which decline with age.
Clinical evidence
NAD+ levels decline significantly with age, falling 50-70% by the seventh decade (Massudi et al., PLOS ONE 2012). This decline is implicated in mitochondrial dysfunction, impaired DNA repair, and accelerated cellular senescence. Yoshino et al. (Cell Metab 2018) demonstrated that NMN supplementation restored mitochondrial function in aged mice. Direct NAD+ injection achieves substantially higher peak serum levels than oral precursors (NR, NMN) and bypasses first-pass metabolism. Clinical studies are emerging, with ongoing trials in cardiovascular disease, neurodegeneration, and aging biomarkers. NAD+ replacement is now considered a foundational longevity-medicine intervention.
Benefits
Dosing
Your prescribing physician determines the right dose, schedule, and how it's administered — based on your goals, medical history, and lab work. Your personalized protocol is provided after your consultation.
Important safety information
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Possible side effects
Do not use if you have
If you experience severe side effects, call 911 or go to your nearest emergency room.
Frequently asked about NAD+ Injection
Most patients notice early effects within 2-4 weeks, with full benefits building over 8-12 weeks of consistent use. Individual response varies based on your goals, baseline health, and dose.
References
- Massudi H, Grant R, Braidy N, et al.. Age-associated changes in oxidative stress and NAD+ metabolism in human tissue · PLOS ONE (2012) · PMID 22848760
- Yoshino J, Baur JA, Imai SI. NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR · Cell Metabolism (2018) · PMID 29249689
- Verdin E. Therapeutic potential of boosting NAD+ in aging and age-related diseases · Science (2015) · PMID 26785480
- Fang EF, Bohr VA, et al.. NAD+ in DNA repair and mitochondrial maintenance · Cell Cycle (2014) · PMID 25192382
Citations are provided for educational purposes. They do not constitute medical advice. Always discuss any peptide protocol with your prescribing physician.
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