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PT-141

Intimacy

PT-141

Intimate wellness

4.8(93 verified reviews)
$279/mo
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This treatment requires licensed provider review and approval. Treatment is not guaranteed. If prescribed, medication is fulfilled by a licensed U.S. pharmacy where permitted by law. Compounded medications are not FDA-approved or FDA-cleared.

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Ships nationwide except CA, AR, KY, AL, SC

About PT-141

Bremelanotide activates melanocortin receptors in the brain to support sexual desire and function.

How it works

PT-141 (Bremelanotide) activates melanocortin-4 receptors in the brain. Unlike Viagra/Cialis (which work on blood flow), PT-141 works on the central nervous system to enhance desire. Effective for both men and women.

Clinical evidence

PT-141 (bremelanotide) was FDA-approved in 2019 under the brand Vyleesi for hypoactive sexual desire disorder (HSDD) in premenopausal women. The RECONNECT trials (Kingsberg et al., Obstet Gynecol 2019) showed statistically significant improvements in desire and reductions in distress vs placebo. Earlier studies in men with erectile dysfunction (Diamond et al., J Sex Med 2006) showed efficacy distinct from PDE5 inhibitors — PT-141 works centrally on melanocortin pathways rather than peripherally on vasodilation, making it useful in patients who don't respond to Viagra or Cialis or whose primary concern is desire rather than erectile function.

Benefits

Enhanced desire
Improved performance
Doctor-supervised
Free shipping

Dosing

Your prescribing physician determines the right dose, schedule, and how it's administered — based on your goals, medical history, and lab work. Your personalized protocol is provided after your consultation.

Important safety information

+

Possible side effects

• Mild nausea (most common)
• Temporary flushing
• Slight headache
• Increase in blood pressure (transient)

Do not use if you have

• Active cancer or history of cancer (unless approved by oncologist)
• Pregnancy or breastfeeding
• Severe kidney or liver disease
• Known allergy to the peptide or excipients
• Uncontrolled hypertension
• Cardiovascular disease

If you experience severe side effects, call 911 or go to your nearest emergency room.

Frequently asked about PT-141

Most patients notice early effects within 2-4 weeks, with full benefits building over 8-12 weeks of consistent use. Individual response varies based on your goals, baseline health, and dose.

References

  1. Kingsberg SA, Clayton AH, Portman D, et al.. Bremelanotide for Hypoactive Sexual Desire Disorder: Two Randomized Phase 3 Trials (RECONNECT) · Obstetrics & Gynecology (2019) · PMID 31403597
  2. Diamond LE, Earle DC, Rosen RC, et al.. Co-administration of bremelanotide with sildenafil in male subjects with erectile dysfunction · Journal of Sexual Medicine (2006) · PMID 16839324
  3. Pfaus JG, Sadiq A, Spitsin S, Douglas SD. Melanocortin receptors and the regulation of sexual function · International Journal of Impotence Research (2008) · PMID 18548080

Citations are provided for educational purposes. They do not constitute medical advice. Always discuss any peptide protocol with your prescribing physician.

Read more about PT-141

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The assessment process available on the [pepti] website asks a series of medical questions, and the answers provided are reviewed by an independent licensed physician affiliated with our partner physician network. The licensed providers have established exclusionary criteria, and the answers provided determine if the individual is screened out of eligibility for treatment. The licensed clinicians retain the sole decision to prescribe peptide therapy and other compounded medications to patients. Treatment may be denied at the physician's sole discretion. If a prescription is not approved, you will not be charged for the medication.

Pharmacy Providers. [pepti] is a technology platform and is not a healthcare provider, pharmacy, or prescriber. All medications offered through the platform are compounded by independent FDA-registered 503A or 503B compounding pharmacies based on a valid prescription written by a licensed physician for an individual patient. Compounded medications are not FDA-approved as products. The active pharmaceutical ingredients used by our partner pharmacies are sourced from FDA-registered facilities. Compounded medications may not undergo the same testing or quality control as commercially manufactured FDA-approved drugs.

Results vary. Results from peptide therapy and other compounded treatments vary based on individual factors, including age, weight, medical history, adherence to the prescribed protocol, lifestyle factors, and physiological response. [pepti] makes no guarantee of any specific outcome. Statements about peptide therapy and compounded medications offered through the platform have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

Product images. Product photographs and renderings shown on this website are for illustrative purposes only. The appearance of vials, packaging, labeling, and other materials you receive may vary and is determined by the dispensing compounding pharmacy.

Off-label use.Many peptides offered through the platform are prescribed for off-label use. “Off-label” means the medication is being prescribed for a use, dose, or patient population that is not specifically approved by the FDA. Off-label prescribing is legal and common in U.S. medical practice when supported by clinical experience and judgment.

Mailing & shipping. All orders ship in plain unmarked packaging via expedited delivery from our partner compounding pharmacies. Temperature-sensitive medications ship with insulated packaging and ice packs. Shipping is included at no additional cost in 45 U.S. states. We do not currently ship internationally or to APO/FPO addresses.

Not for emergencies. [pepti] is not designed for medical emergencies. If you are experiencing a medical emergency, call 911 or go to your nearest emergency room immediately. For urgent but non-emergency medical questions, contact your primary care provider or use an urgent care service.

No doctor-patient relationship with [pepti]. Your use of the platform does not create a doctor-patient relationship between you and pepti LLC. A doctor-patient relationship is established only between you and the independent licensed physician who reviews your intake and prescribes your treatment. The physicians who use the platform are independent contractors and are solely responsible for the medical care they provide.

Prescription medications. All prescription products require a valid prescription from a licensed healthcare provider. By using the platform, you acknowledge that you are at least 18 years old and that the information you provide is true, accurate, current, and complete. Providing false information may result in inappropriate treatment recommendations or denial of service.

Cosmetic & wellness products.Certain products offered through [pepti] — including skincare, hair care, body care, supplements, men's grooming, sports recovery, and sexual wellness products — are cosmetic or dietary supplement products, not prescription medications. These products do not require a prescription and are not reviewed or prescribed by a physician. Statements regarding dietary supplements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. Results vary by individual. Consult your healthcare provider before starting any new supplement or topical product, especially if you are pregnant, nursing, or taking other medications.

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